Isaah Yeo has been instrumental in the success of the Panthers this year, and his Mudgee-based parents, Justin and Amy Yeo, couldn't be more proud.

"As parents, we're really happy with where he's at. He's about to be a dad so it's been an exciting year for him," Justin and Amy said.

"We're hoping for a victory but it's going to be a very tough game. The last time they played Souths they lost, so they're obviously going to have to play their best. It's the time of year where anything can happen.

"He's got a lot of family in Mudgee and Dubbo who will be watching him. He's going to represent the Central West and his family."

As a former North Sydney and Balmain centre, the 26-year-old's father, Justin knows what it takes to get the result, and said his son's combination with Panthers co-captain, Nathan Cleary has proved worthy.

Should the duo pull it off, this will be the club's first premiership since 2003.

"They've [Yeo and Cleary] got a really good relationship and it works really well. The boys they lead have such respect for them," Justin said.

"I think he likes to try to lead by example so his effort is always 100 per cent," Isaah's mother, Amy said.

"He'll come off and tell us how completely exhausted he was and that he didn't think he would get through it but he always lifts and he does."

With three younger siblings, Yeo remains a source of inspiration for the family, especially for one of his sisters who hopes to take up the sport next year.

"His second youngest sister is very football orientated as well, she's looking at playing some rugby league down in Sydney when she gets to uni next year," Amy said.

"She watches his games with a little more interest than his other sister, quite possibly, but they are all very proud of him."

With hopes for a victory, the Yeos are confident that if anybody can lead a team to a premiership title, it's Isaah.

"When Isaah first became captain, he said 'you can't ask people to do something if you're not willing to do it yourself', so he'll be very busy and he's going to be tired by the end of it," they said.

"He'll do a good job. Fingers crossed they get the result."

The Penrith Panthers will take on the South Sydney Rabbitohs in the 2021 NRL grand final on Sunday, October 3.

Kick-off will be at 7.30pm.

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