Emergency services were called to a single vehicle accident at approximately 7pm last night on Cope Road, Gulgong.
When police arrived on the scene, the sole occupant was trapped inside the vehicle requiring emergency services to remove the door in order for the woman to be treated on scene before being transported to Mudgee Hospital.
The driver was then flown to St George Hospital where she remains in a serious condition having suffered severe injuries to the chest and head.
Police are appealing for any witnesses who saw the four-wheel drive Pajero travelling along Cope Road last night.
“It was raining so Police are inspecting the circumstances around how the accident occurred,” Inspector Mark Fehon said.
“We ask that every body drive to the conditions of the road. If it is wet, please take care.”
If anyone has any information, please contact Mudgee Police or Crime Stoppers.